Monday 30 November 2015

26 November 2015 - Neurosciences Outpatients Dept, QE Hospital


Deb in Dubrovnik, September 2015


It is over 6 months since I last posted. During that time Deb has had two more MRI scans (32nd and 33rd since her radiotherapy treatment).  The results of both these scans were good, with no visible change in the tumour detected. We saw Dr Sanghera and Fred who were both very relaxed.  It is now 7.5 years since Deb was diagnosed. It is very, very unusual for patients with a glioblastoma brain tumour to survive this long. Usually the radio/chemotherapy stops the tumour growth for a short while but cancer growth soon returns. The path taken by the disease with Deb has been different with no progression after her debaulking operation. Dr Sanghera said there were no medical protocols for patients who have lived this long. However he has suggested that the period between scans could now be increased to 4 months initially and provided there was no change in the tumour this period eventually could be extended to 6 months. Deb was really buoyed up be this news. if the doctors are getting more relaxed then so can we.

It seems pointless for me to keep putting up blog after blog saying nothing has changed. So I propose that from now on I will not put up any futher posts until there is something to report.

Have a merry Christmas and a happy new year. Chris

Monday 9 March 2015

26 February 2015 - Neurosciences Outpatients Department, QE Hospital






Deb had her latest MRI scan on 8 February (a normal MRI scan - her 31st since radiotherapy). The results from the scan were good.  The tumour size, compared with the previous scan, was unchanged. There were none of the signs of activity as reported in the previous 2 or 3 scans. Whether the increased activity seen previously was real or not is not clear; in any case we can relax again.

On the 28 January, Deb and I attended a Brain Tumour Information Day organised by the Brain Tumour Charity. One of the speakers was Professor Cruickshank, Professor of Neurosurgery at the QE, During his talk he showed the above graph which gives an estimate, for patients with a glioblastoma  tumour, of the numbers  still living a certain amount of time after treatment. The red line is for patients who have radiotherapy alone and the blue line is for patients who receive radiotherapy and the chemotherapy drug temozolomide (like Deb). As you can see only about 20%, ie 1 in 5, patients will survive 3 years or more.  What interested me was the fact that after 3 years the graph appeared to be flat which seems to imply that the number of deaths after 3 years is greatly reduced. I asked Dr Sanghera about this. What does the graph look like at 5, 6 or (like Deb) at 7 years? He said he didn't know; the research had not been done. What we do know is if you survive 5 years then your chances of surviving a further 5 years are greatly improved.